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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 17 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MRP3/ABCC3 Rabbit Polyclonal Antibody detects endogenous levels of MRP3/ABCC3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MRP3 also known as ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. MRP3 plays a crucial role in the cellular export of organic anions, particularly in the liver, where MRP3 is predominantly expressed at the basolateral membrane of hepatocytes. This localization is significant because MRP3 facilitates the transport of various endogenous and exogenous compounds, including drugs and metabolites, from the liver into the bloodstream. MRP3 expression regulation is particularly important in the context of drug resistance, as MRP3 levels can increase when the function of other transporters, such as MRP2, is compromised. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat cells, using MRP3/ABCC3 Rabbit Polyclonal Antibody (EAB11389) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human breast cancer tissue, using MRP3/ABCC3 Rabbit Polyclonal Antibody (EAB11389) at 1:200 dilution.
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