| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | IHC-P, IF/ICC, ELISA | 218 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CHD4 Rabbit Polyclonal Antibody detects endogenous levels of CHD4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CHD4 also known as Mi-2b, Mi2-BETA belongs to the SNF2/RAD54 helicase family. CHD4 plays a significant role in gene expression regulation by mediating histone deacetylation. CHD4′s ability to recruit histone deacetylases, such as HDAC1 and HDAC2, is vital for maintaining the balance between gene activation and repression, making CHD4 essential for proper cellular function and development. Dysregulation of CHD4 and associated complexes can lead to various diseases, including cancer, highlighting the importance of studying CHD4 in understanding transcriptional regulation and disease implications. |
| Product Image Gallery | |
 Immunohistochemistry of paraffin-embedded Human liver cancer tissue, using CHD4 Rabbit Polyclonal Antibody (EAB13050) at 1:100 dilution.
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