| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, FC, ELISA | 98 | Human, Mouse, Rat, Pig |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IF/ICC=1:100-500 FC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TLR5 Mouse Monoclonal Antibody detects endogenous levels of TLR5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TLR5 also known as TIL3, SLEB1 is a member of the toll-like receptor (TLR) family. TLR5 plays a crucial role in the innate immune system by recognizing bacterial flagellin, which is a key component of bacterial flagella. This recognition triggers a signaling cascade that leads to the activation of immune responses, including the production of pro-inflammatory cytokines. TLR5′s ability to detect flagellated bacteria is vital for initiating an effective immune response, thereby helping to protect the host from infections. TLR5 is predominantly expressed in immune cells, particularly in monocytes, and is also found in tissues such as the ovary, prostate, and testis. Expression in these areas underscores TLR5′s importance in both local and systemic immune responses, making TLR5 a significant target for research in immunology and infectious diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549, Raw264.7 cells, using TLR5 Mouse Monoclonal Antibody (EAB22708) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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