ACSL1 Rabbit Monoclonal Antibody
Catalog #:EAB21172
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Monoclonal WB, IHC-P, IF/ICC 78 Human
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:1000-5000 
IHC-P=1:100-500 
IF/ICC=1:100-500
Product Information
Conjugate Unconjugate
Specificity ACSL1 Rabbit Monoclonal Antibody detects endogenous levels of ACSL1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P33121

Entrez Gene ID

2180

Product Description

ACSL1(Acyl-CoA synthetase long chain family member 1) is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. ACSL1 plays a crucial role in lipid metabolism, specifically in the activation of long-chain fatty acids to acyl-CoA derivatives, which are essential for various metabolic pathways, including the synthesis of cellular lipids and the β-oxidation process. This activation allows fatty acids to be utilized for energy production and the formation of important biomolecules such as triacylglycerols, phospholipids, and cholesteryl esters. ACSL1 is predominantly expressed in the liver and exhibits a preference for substrates like palmitoleate, oleate, and linoleate, highlighting its significance in maintaining lipid homeostasis and energy balance within the body. ACSL1′s ability to interact with various long-chain fatty acids underscores its importance in metabolic regulation and potential implications in metabolic disorders.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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