| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 160 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BAF170 Rabbit Polyclonal Antibody detects endogenous levels of BAF170 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BAF170 also designated SMARCC2 is a member of the SWI/SNF family of proteins. BAF170 plays a vital role in regulating gene expression by altering nucleosome structure in an ATP-dependent manner. BAF170 within the complex is essential for remodeling activity, interacting with other core subunits such as Brg-1 and Ini1 to enhance overall SWI/SNF complex function. This interaction enables precise regulation of transcriptional activation, critical for various cellular processes, including differentiation and response to environmental signals. BAF170′s involvement in chromatin remodeling underscores BAF170′s importance in maintaining cellular homeostasis and potential implications in cancer biology, where dysregulation of chromatin remodeling can lead to aberrant gene expression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293T, 22RV1, HepG2 cells, using BAF170 Rabbit Polyclonal Antibody (EAB11346) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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