| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, FC | 90 | Human, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:100-500 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Calnexin Rabbit Monoclonal Antibody detects endogenous levels of Calnexin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Calnexin also known as CNX, IP90, CANX is a member of the calnexin family of molecular chaperones. As a type I integral membrane protein, Calnexin plays a crucial role in the quality control system of the ER by interacting with newly synthesized N-linked glycoproteins, ensuring their proper folding and assembly. This function is important because it prevents the accumulation of misfolded proteins, which can lead to cellular stress and diseases such as neurodegeneration. Calnexin binds to monoglucosylated glycoproteins, retaining them in the ER until they achieve their correct conformation. By facilitating the maturation of glycoproteins, Calnexin maintains protein homeostasis within the cell. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, HepG2 cells, using Calnexin Rabbit Monoclonal Antibody (EAB22540) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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