| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 41 | Human, Mouse, Rat, Pig |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PKA C Rabbit Polyclonal Antibody detects endogenous levels of PKA C protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PKA C is a critical cAMP-dependent enzyme that orchestrates a wide range of cellular functions, including regulation of cell proliferation, ion transport, metabolism, and gene transcription. By phosphorylating specific target proteins, PKA C modulates key signaling pathways that are essential for maintaining cellular homeostasis and responding to external stimuli. The catalytic subunits of PKA C become active upon binding of cyclic AMP to the regulatory subunits, leading to their dissociation and subsequent translocation to various cellular compartments where they execute phosphorylation of substrates involved in diverse biological processes. The proper functioning of PKA is vital for numerous physiological processes, and its dysregulation is associated with various diseases such as cancer, diabetes, and neurological disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 22RV1, Mouse colon cells, using PKA C Rabbit Polyclonal Antibody (EAB11308) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human brain tissue, using PKA C Rabbit Polyclonal Antibody (EAB11308) at 1:200 dilution.
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