| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 142 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | COL2A1 Rabbit Monoclonal antibody detects endogenous levels of COL2A1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
COL2A1 also konwn as Collagen II alpha 1 a fibrillar collagen found in cartilage and the vitreous humor of the eye. COL2A1 plas a crucial component of cartilage that provides structural support and resilience to joints. COL2A1 is primarily located in cartilage, where COL2A1 forms the structural framework essential for maintaining tissue integrity and resilience. This localization is crucial because cartilage serves as a cushion between bones in joints, providing support and flexibility while absorbing shock during movement. COL2A1 is vital for proper functioning of articular cartilage, and COL2A1 degradation is associated with various joint disorders, including osteoarthritis and rheumatoid arthritis. The unique triple helix structure of COL2A1 allows for withstanding tensile forces, making COL2A1 a key player in cartilage mechanical properties. |
| Product Image Gallery | |
 Western blot analysis of extracts on SW1351, A431 cells, using COL2A1 Rabbit Monoclonal Antibody (EAB22550) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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