| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 23 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DNAJC12 Rabbit Polyclonal Antibody detects endogenous levels of DNAJC12 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DNAJC12 also known as JDP1 is a member of a subclass of the HSP40/DnaJ protein family. DNAJC12 is a J-domain co-chaperone that partners with HSP70 machinery to regulate protein folding and proteostasis within the cytosol and endoplasmic reticulum. By stimulating HSP70 ATPase activity, DnaJC12 supports maturation and stability of client proteins and helps coordinate cellular responses to proteotoxic stress. This chaperone network interfaces with ubiquitin–proteasome and ER-associated degradation pathways to maintain protein quality control. Altered DNAJC12 function has been linked to disrupted enzyme homeostasis and neuro-metabolic phenotypes, making it relevant for studying stress adaptation and protein maturation pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431 cells, using DNAJC12 Rabbit Polyclonal Antibody (EAB11212) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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