| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 70 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PPP2R5D Rabbit Polyclonal Antibody detects endogenous levels of PPP2R5D protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PPP2R5D also known as PP2A-B56-δ, B56δ, B56delta is a member of the phosphatase 2A regulatory subunit B family. PPP2R5D plays a crucial role in various cellular processes, including cell growth, division, and apoptosis. PPP2R5D modulates PP2A holoenzyme activity through a trimeric complex composed of regulatory, variable, and catalytic subunits. PPP2R5D specifically influences substrate specificity and cellular localization, impacting target protein dephosphorylation in critical signaling pathways. PPP2R5D interactions with other subunits form distinct PP2A complexes targeting specific substrates, maintaining cellular homeostasis and responding to stress signals. PPP2R5D regulates diverse cellular functions, highlighting significance in normal physiology and disease states, including cancer, where phosphatase activity dysregulation can lead to aberrant signaling and tumor progression. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, Jurkat, 293T cells, using PPP2R5D Rabbit Polyclonal Antibody (EAB12063) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human brain tumor tissue, using PPP2R5D Rabbit Polyclonal Antibody (EAB12063) at 1:200 dilution.
 Immunofluorescence analysis of Siha cell, using PPP2R5D Rabbit Polyclonal Antibody (EAB12063) at 1:100 dilution.
|
