| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC, FC | 42 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CD62L/L-Selectin Rabbit Monoclonal Antibody detects endogenous levels of CD62L/L-Selectin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
L-Selectin also known as also CD62L, LECAM-1, SELL is a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. L-Selectin plays a crucial role in the immune response by mediating the adhesion of leukocytes to the endothelium, which is essential for the migration of immune cells to sites of inflammation. L-Selectin is predominantly expressed on the surface of naive T cells, B cells, and various types of leukocytes, including monocytes, neutrophils, and eosinophils. L-Selectin′s ability to interact with specific carbohydrates on activated endothelial cells facilitates the initial steps of leukocyte extravasation, a process vital for effective immune surveillance and response. The structural features of L-Selectin, including its lectin-like domain, are important for binding affinity and specificity to ligands such as sialyl-Lex, which are expressed on activated endothelial cells. |
| Product Image Gallery | |
 Western blot analysis of extracts on Human serum cells, using CD62L/L-Selectin Rabbit Monoclonal Antibody (EAB22382) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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