| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IP, IHC-P, IF/ICC, ELISA | 91 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:100-500 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CD62P/P-Selectin Mouse Monoclonal Antibody detects endogenous levels of CD62P/P-Selectin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
P-Selectin also designated CD62P, GMP-140, SELP is a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. P-Selectin plays a crucial role in the inflammatory response by mediating the adhesion of leukocytes to activated endothelial cells and platelets, which is essential for the recruitment of immune cells to sites of injury or infection. P-Selectin is primarily located on the surface of activated platelets and endothelial cells, where P-Selectin facilitates the rolling and adhesion of leukocytes, a critical step in the immune response. Proper functioning of P-Selectin is vital for maintaining vascular integrity and ensuring effective immune surveillance, making P-Selectin a significant target for research in inflammation and cardiovascular diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, Jurkat cells, using CD62P/P-Selectin Mouse Monoclonal Antibody (EAB21187) at 1:3000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 91 kDa; Observed band size: 105, 140 kDa |
