| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 46 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NK-1R Rabbit Polyclonal Antibody detects endogenous levels of NK-1R protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NK-1R also known as TACR1 is a member of the tachykinin receptor family, which includes NK-2 and NK-3 receptors, and plays a significant role in various physiological processes. NK-1R is primarily located in the central nervous system, particularly in the dorsal horn of the spinal cord, where NK-1R is expressed in a high proportion of spinothalamic and spinobranchial neurons. NK-1R localization is crucial as NK-1R is involved in nociceptive transmission, influencing pain perception and the modulation of chronic neuropathic and inflammatory pain. Furthermore, NK-1R′s interaction with tachykinin peptides, such as substance P, substance K, and neuromedin K, highlights NK-1R′s importance in mediating responses related to anxiety and depression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, Mouse brain cells, using NK-1R Rabbit Polyclonal Antibody (EAB11189) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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