| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 47 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Cytokeratin 18 (Ser52) Rabbit Polyclonal Antibody detects endogenous levels of Cytokeratin 18 protein only when phosphorylated at Ser52. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cytokeratin 18 also known as CK-18, Keratin 18, KRT18 is a vital component of the cytoskeleton in epithelial cells, Cytokeratin 18 playing a crucial role in maintaining cell integrity and providing mechanical support. Cytokeratin 18 is primarily located in the cytoplasm of epithelial cells, where proper localization is essential for cellular architecture and function. Disruption of Cytokeratin 18 localization can lead to compromised cell stability and has been implicated in various pathological conditions, including cancer. Cytokeratin 18 serves as a significant marker for adenocarcinomas and basal cell carcinomas, making Cytokeratin 18 an important target for cancer diagnostics and research. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, NIH/3T3 cells, using Phospho-Cytokeratin 18 (Ser52) Rabbit Polyclonal Antibody (EAB11167) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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