| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 62 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ENL/MLLT1 Rabbit Polyclonal Antibody detects endogenous levels of ENL/MLLT1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ENL also known as MLLT1 is capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells. ENL plays a crucial role in transcriptional regulation and is involved in the formation of MLL fusion proteins, which are significant in the context of leukemia. ENL interacts with several key partners, including the MLL gene, which influences myelomonocytic differentiation. Fusion of ENL with MLL, resulting from chromosomal translocations, leads to the production of MLL-ENL fusion protein, commonly associated with infant acute leukemias. This interaction alters normal gene expression patterns, contributing to the pathogenesis of various leukemias. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using ENL/MLLT1 Rabbit Polyclonal Antibody (EAB11440) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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