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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 48 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IFRD2 Rabbit Polyclonal Antibody detects endogenous levels of IFRD2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IFRD2(Interferon-related developmental regulator 2) also known as SKMc15 is a 442 amino acid soluble nuclear protein that plays a crucial role in cellular processes. IFRD2 is ubiquitously expressed and features a β-catenin-like repeat, suggesting involvement in the adenomatous polyposis coli (APC) signaling pathway, which is vital for regulating cell growth and differentiation. IFRD2 shares 75% homology with IFRD1 and may influence the expression of surface adhesion molecules essential for the differentiation and fusion of myogenic satellite cells, which are critical for muscle regeneration. While the gene encoding IFRD2 is subject to overlapping homozygous deletions in various lung cancer cell lines, IFRD2 does not exhibit loss-of-function mutations in cancer cells, indicating a potential role in tumor progression and highlighting importance in cancer biology. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293, Raw264.7 cells, using IFRD2 Rabbit Polyclonal Antibody (EAB11415) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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