| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 24 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rab4 Rabbit Monoclonal Antibody detects endogenous levels of Rab4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rab4 also known as RAB4A is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. Rab4 plays a crucial role in the regulation of endosomal trafficking, particularly in the recycling of proteins from endosomes back to the plasma membrane, which is essential for maintaining cellular homeostasis and membrane composition. This recycling process is vital for various cellular functions, including nutrient uptake, receptor signaling, and the removal of damaged proteins, thereby influencing cell survival and function. The proper functioning of Rab4 is also linked to the prevention of diseases associated with dysfunctional endosomal transport, such as neurodegenerative disorders and certain cancers. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse brain cells, using Rab4 Rabbit Monoclonal Antibody (EAB22564) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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