| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 118 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Angiomotin Rabbit Polyclonal Antibody detects endogenous levels of Angiomotin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Angiomotin also known as AMOT is a 1,084 amino acid protein belonging to the motin family of angiostatin-binding proteins, characterized by conserved coiled-coil domains and PDZ binding motifs at their C-termini. Angiomotin is primarily expressed in skeletal muscle and placenta, where Angiomotin localizes to the cell surface at tight junctions, playing a crucial role in maintaining these structures. Angiomotin′s interaction with angiostatin is vital for angiogenesis, as Angiomotin promotes tubule formation and enhances the migration of endothelial cells in response to growth factors. This function underscores Angiomotin′s potential as a key player in tumor angiogenesis, making Angiomotin a promising therapeutic target in cancer treatment. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293 cells, using Angiomotin Rabbit Polyclonal Antibody (EAB11418) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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