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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 28 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HoxB4 Rabbit Polyclonal Antibody detects endogenous levels of HoxB4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HoxB4(Homeobox B4) also known as HOX2F is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. HoxB4 plays a crucial role in regulating hematopoietic stem cell dynamics, balancing self-renewal and differentiation. This regulation is vital for maintaining proper blood cell development and tissue homeostasis. HoxB4′s function is influenced by interactions with transcription factors such as USF-1 and USF-2, which are modulated by cytokines that promote stem cell self-renewal. Additionally, HoxB4 depends on AP-1 expression to drive changes in cellular proliferation and differentiation, which elevates cyclin D1 levels, linking HoxB4 to essential components of the cell cycle machinery. |
| Product Image Gallery | |
 Western blot analysis of extracts on HT29 cells, using HoxB4 Rabbit Polyclonal Antibody (EAB11149) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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