www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 85 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Fyb Rabbit Polyclonal Antibody detects endogenous levels of Fyb protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Fyb(Fyn binding protein) also known as ADAP, SLAP130 is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. Fyb plays a crucial role in T cell signaling by interacting with tyrosine kinase p59fyn and anchoring proteins such as SKAP55 and SKAP55-R. These interactions are vital for regulating signaling events initiated by lymphocyte antigen receptors, which ultimately lead to T cell activation. Fyb protein is located in the cytoplasm and is involved in assembling signaling complexes that facilitate communication between T cells and their environment. Human Fyb gene is located on chromosome 5p13.1 and encodes a 783 amino acid protein, which is essential for maintaining proper immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on COLO205, Jurkat cells, using Fyb Rabbit Polyclonal Antibody (EAB11120) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
