www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 32 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HEXIM2 Rabbit Polyclonal Antibody detects endogenous levels of HEXIM2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HEXIM2 is a member of the HEXIM family of proteins. HEXIM2 is a component of the 7SK small nuclear ribonucleoprotein. HEXIM2 plays a crucial role in regulating transcription elongation by inhibiting the Positive Transcription Elongation Factor b (P-TEFb) complex, which is essential for proper expression of eukaryotic genes. P-TEFb, composed of catalytic subunit Cdk9 and regulatory subunits Cyclin T1 or T2, is vital for transitioning RNA polymerase II into the elongation phase of transcription. By binding to 7SK small nuclear ribonucleic acid particle, HEXIM2 helps maintain the balance of transcriptional activity, preventing excessive gene expression that could lead to cellular dysfunction. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using HEXIM2 Rabbit Polyclonal Antibody (EAB11207) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
