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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 60 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Epsin 1 Rabbit Polyclonal Antibody detects endogenous levels of Epsin 1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Epsin 1 also known as EPN1 is a member of the epsin protein family. Epsin 1 plays a crucial role in the endocytic process, particularly in forming Clathrin-coated vesicles, which are essential for membrane proteins and lipids internalization. Epsin 1 is primarily located at the leading edge of vesicular coated pits, where Epsin 1 facilitates membrane bending, a critical step in endocytosis. This localization ensures efficient uptake of extracellular materials and signaling molecules, thereby influencing cellular communication and nutrient absorption. Epsin 1 also interacts with key proteins such as Eps15 and Clathrin, and Epsin 1 function is regulated by post-translational modifications, including phosphorylation, which can modulate activity during different cellular states, such as mitosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, Mouse brain cells, using Epsin 1 Rabbit Polyclonal Antibody (EAB11105) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 60 kDa; Observed band size: 85 kDa |
