| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 162 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CLIP170 Rabbit Polyclonal Antibody detects endogenous levels of CLIP170 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CLIP170 also known as CLIP1 is the original member of a group of microtuble binding proteins. CLIP170 plays a crucial role in cellular dynamics as a member of the plus-end-binding proteins (+TIPs), which are essential for microtubule stabilization and organization. By binding to the growing plus ends of microtubules, CLIP170 acts as a linker between these dynamic structures and organelle membranes, thereby promoting microtubule rescue and preventing catastrophe, particularly near the cell periphery. This function is vital for maintaining cellular integrity and facilitating intracellular transport, as CLIP170 ensures that microtubules remain stable and functional during cellular processes such as mitosis and organelle movement. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, A549, Jurkat cells, using CLIP170 Rabbit Polyclonal Antibody (EAB11072) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
