| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 62 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CRMP-3 Rabbit Polyclonal Antibody detects endogenous levels of CRMP-3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CRMP-3 also known as DRP-4, DPYSL4 is a cytosolic phosphoprotein in the CRMP family that links extracellular guidance cues to microtubule dynamics and cytoskeletal remodeling. CRMP-3 has been implicated in neurite outgrowth, axon guidance, and regulation of cellular morphology through signaling pathways downstream of semaphorins and related kinases that modulate CRMP phosphorylation states. Beyond neural contexts, CRMP-3 expression has been associated with stress-adaptive programs and metabolic rewiring, connecting it to processes such as mitochondrial function, motility, and cell survival. Dysregulated CRMP-3 signaling has been reported in studies of neurological disorders and cancer-associated phenotypes, supporting its utility as a mechanistic target for pathway interrogation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Raw264.7, LOVO, HT29 cells, using CRMP3 Rabbit Polyclonal Antibody (EAB14442) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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