| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 87 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Integrin β3 Mouse Monoclonal Antibody detects endogenous levels of Integrin β3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Integrin β3 also known as CD61, ITGB3 is a crucial component of integrin receptors, which are heterodimers formed by the noncovalent association of α and β subunits. Integrin β3 mediates cell adhesion and signaling by interacting with ligands in the extracellular matrix, such as fibronectin and collagen, as well as soluble ligands like fibrinogen. These interactions drive various cellular processes, including cell migration, growth, and differentiation. Integrin β3 enables platelet activation and plays a significant role in hemostasis and thrombosis, making Integrin β3 a key target for therapeutic interventions in cardiovascular diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc cells, using Integrin β3 Mouse Monoclonal Antibody (EAB22383) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 87 kDa; Observed band size: 70 kDa |
