| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC | 37 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BCL2L14/Bcl-G Mouse Monoclonal Antibody detects endogenous levels of BCL2L14/Bcl-G protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Bcl-G also known as BCL2L14 is a member of the BCL2 protein family. Bcl-G plays a crucial role in regulating apoptosis, a process essential for maintaining cellular homeostasis and eliminating damaged or unwanted cells. Bcl-G is expressed in three alternatively spliced isoforms: short, medium, and long, with the short isoform being testis-specific and localized to cytosolic organelles, while the long isoform is more widely distributed throughout the cytosol. Bcl-G′s ability to induce apoptosis upon overexpression highlights a potential role in tumor suppression, making Bcl-G a significant target for research in cancer biology. Understanding Bcl-G function and regulation is vital for developing therapeutic strategies aimed at modulating apoptosis in various diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, A549, Rat brain cells, using BCL2L14/Bcl-G Mouse Monoclonal Antibody (EAB22387) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 37 kDa; Observed band size: 52 kDa |
