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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 46 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HSP47/SERPINH1 Rabbit Polyclonal Antibody detects endogenous levels of HSP47/SERPINH1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HSP47 also known as CBP1, SERPINH1 is a crucial molecular chaperone that plays a significant role in the biosynthesis of collagen type I. HSP47 is predominantly located in the endoplasmic reticulum of cells that produce procollagen, where HSP47 assists in the proper folding and assembly of collagen molecules, ensuring their structural integrity and functionality. HSP47′s location is essential for the secretion of procollagen from these cells, thereby influencing the extracellular matrix formation and tissue repair processes. Additionally, HSP47 acts as a stress response molecule, sequestering abnormal procollagen following cellular insult, which highlights HSP47′s protective role in maintaining collagen homeostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on DU145 cells, using Phospho-HSP47/SERPINH1 Rabbit Polyclonal Antibody (EAB11876) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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