| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, ELISA | 39 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:5000-20000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CK1 alpha Mouse Monoclonal antibody detects endogenous levels of CK1 alpha protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CK1 alpha also known as Casein Kinase I alpha, CK1, CSNK1A1 is a member of the protein kinase superfamily. CK1 alpha plays a crucial role in several cellular processes, including the regulation of the Wnt signaling pathway, which is vital for cell proliferation and differentiation. CK1 alpha is primarily located in the cytoplasm, where CK1 alpha is involved in the phosphorylation of various substrates, thereby influencing key signaling pathways that govern cellular functions such as DNA repair, circadian rhythms, and apoptosis. Casein kinase I alpha′s ability to modulate these pathways underscores CK1 alpha′s importance in maintaining cellular homeostasis and potential implications in various diseases, including cancer and neurodegenerative disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, HEK293, NIH/3T3 cells, using CK1 alpha Mouse Monoclonal antibody (EAB22525) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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