| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 39 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CK1 alpha Rabbit Polyclonal Antibody detects endogenous levels of CK1 alpha protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CK1 alpha also known as Casein Kinase I alpha, CK1, CSNK1A1 is a member of the protein kinase superfamily. CK1 alpha plays a crucial role in several cellular processes, including the regulation of the Wnt signaling pathway, which is vital for cell proliferation and differentiation. CK1 alpha is primarily located in the cytoplasm, where CK1 alpha is involved in the phosphorylation of various substrates, thereby influencing key signaling pathways that govern cellular functions such as DNA repair, circadian rhythms, and apoptosis. CK1 alpha′s ability to modulate these pathways underscores CK1 alpha′s importance in maintaining cellular homeostasis and potential implications in various diseases, including cancer and neurodegenerative disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HT29 cells, using CK1 alpha Rabbit Polyclonal Antibody (EAB11046) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 39 kDa; Observed band size: 35 kDa  Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using CK1 alpha Rabbit Polyclonal Antibody (EAB11046) at 1:100 dilution.
 Immunofluorescence analysis of Hela cell, using CK1 alpha Rabbit Polyclonal Antibody (EAB11046) at 1:100 dilution.
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