| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 12 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MPC1 Rabbit Polyclonal Antibody detects endogenous levels of MPC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MPC1 also known as BRP44L is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. MPC1 a core component of the MPC complex that transports cytosolic pyruvate across the inner mitochondrial membrane to fuel the TCA cycle and oxidative phosphorylation. By regulating pyruvate entry, MPC1 influences glycolysis–mitochondria coupling, anaplerosis, and metabolic flexibility during nutrient stress and differentiation. Altered MPC1 activity has been linked to rewired cellular energetics observed in proliferative states and mitochondrial metabolic disorders, with downstream effects on redox balance and biosynthetic pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, COLO205 cells, using MPC1 Rabbit Polyclonal Antibody (EAB11002) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human heart tissue, using MPC1 Rabbit Polyclonal Antibody (EAB11002) at 1:100 dilution.
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