| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 15 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IFITM3 Rabbit Polyclonal Antibody detects endogenous levels of IFITM3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IFITM3(Interferon induced transmembrane protein 3) is an interferon-stimulated restriction factor that localizes mainly to endosomal and lysosomal membranes, where it modulates membrane properties to limit viral entry and fusion. It functions downstream of type I and type II interferon signaling, linking innate immune sensing to cellular antiviral defenses and influencing endocytic trafficking and membrane remodeling. IFITM3 activity has been studied extensively in the context of respiratory virus susceptibility and severity, including influenza virus and coronaviruses, and it can shape inflammatory responses in infected tissues. Beyond infection biology, altered IFITM3 expression has been associated with tumor cell invasion, immune microenvironment interactions, and stress-adaptive programs, making it relevant for studies of immuno-oncology and cell-intrinsic defense pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using IFITM3 Rabbit Polyclonal Antibody (EAB11023) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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