GβL Rabbit Polyclonal Antibody
Catalog #:EAB11014
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, ELISA 36 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity GβL Rabbit Polyclonal Antibody detects endogenous levels of GβL protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q9BVC4

Entrez Gene ID

64223

Product Description

GβL also known as GbetaL, LST8, GBL, MLST8 is integral to the function of heterotrimeric G proteins, which are essential for transmitting signals from cell surface receptors to various intracellular effectors. GβL plays a crucial role in regulating the mTOR signaling pathway, which is essential for cellular growth, proliferation, and survival. Through interactions with mTOR and other components of the signaling cascade, GβL helps modulate cellular response to nutrients and growth factors, making GβL vital for maintaining cellular homeostasis and influencing metabolic processes. GβL′s primary function is to stabilize the mTOR complex, This regulation is particularly important in cancer research, as dysregulation of the mTOR pathway is often implicated in tumorigenesis.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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