| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 35 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AQP4 Mouse Monoclonal Antibody detects endogenous levels of AQP4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AQP4(Aquaporin 4) is a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. AQP4 plays a crucial role in regulating water homeostasis in the body, particularly in the central nervous system and skeletal muscle. AQP4 is predominantly localized to the sarcolemma of fast-twitch muscle fibers, where AQP4 facilitates rapid water transport, essential for muscle contraction and recovery. AQP4 presence in the brain is vital for maintaining water balance in the extracellular space, which is critical for neuronal function and overall brain health. AQP4 dysregulation has been implicated in various neurological disorders, making AQP4 a significant target for research in understanding and treating conditions such as edema and multiple sclerosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse Heart, Rat Heart cells, using AQP4 Mouse Monoclonal Antibody (EAB11647) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 35 kDa; Observed band size: 48 kDa  Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using AQP4 Mouse Monoclonal Antibody (EAB11647) at 1:500 dilution.
 Immunofluorescence analysis of Hela cell, using AQP4 Mouse Monoclonal Antibody (EAB11647) at 1:100 dilution.
|
