| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 99 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ALDH1L1 Rabbit Monoclonal Antibody detects endogenous levels of ALDH1L1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ALDH1L1 also known as FTHFD, 10-FTHFDHplays a crucial role in cellular metabolism by catalyzing the conversion of 10-formyltetrahydrofolate to tetrahydrofolate, a vital cofactor in the synthesis of nucleotides and amino acids. This enzymatic activity helps regulate cellular levels of tetrahydrofolate, which is essential for DNA synthesis and repair, thereby influencing cell proliferation and growth. ALDH1L1 is developmentally regulated in the cerebellum, indicating potential involvement in neurodevelopmental processes. ALDH1L1 overexpression has been shown to restrict cell proliferation in vitro, suggesting a tumor suppressor role in certain contexts. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse brain cells, using ALDH1L1 Rabbit Monoclonal Antibody (EAB22074) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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