| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 63 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cdc6 Rabbit Polyclonal Antibody detects endogenous levels of Cdc6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cdc6(Cell division cycle 6) is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. Cdc6 plays a crucial role in the initiation of DNA replication, which is essential for cell division and proper progression of the cell cycle. By ensuring DNA replication occurs at the right time, Cdc6 helps maintain genomic stability and prevents errors that could lead to cell malfunction or disease. Cdc6 is particularly important in cancer research, as dysregulation of Cdc6 can contribute to uncontrolled cell proliferation. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, and interaction with various proteins, such as Cdc37, aids in the formation of the cyclin D1/Cdk4 complex, highlighting an integral role in cell cycle regulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, HepG2 cells, using Cdc6 Rabbit Polyclonal Antibody (EAB11700) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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