www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, ELISA | 60 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HSP60 Mouse Monoclonal Antibody detects endogenous levels of HSP60 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HSP60 also known as HSPD1 is a key member of the heat shock protein family. HSP60 plays a crucial role in mitochondrial function, acting as a molecular chaperone that assists in proper folding and assembly of newly synthesized proteins destined for the mitochondrial matrix. HSP60 is essential for maintaining cellular homeostasis, particularly under stress conditions, as HSP60 helps prevent aggregation of misfolded proteins, which can lead to cellular dysfunction and disease. HSP60 is located in both mitochondria and cytosol, highlighting HSP60′s importance in cellular processes that require transport and proper folding of polypeptides across membranes. HSP60′s ability to interact with various client proteins underscores HSP60′s significance in cellular stress responses and potential as a therapeutic target in diseases associated with protein misfolding. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293, Mouse kidney, Rat heart cells, using HSP60 Mouse Monoclonal Antibody (EAB14637) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
|
