| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC, FC | 281 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Filamin A Rabbit Monoclonal Antibody detects endogenous levels of Filamin A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Filamin A also known as Filamin 1, FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Filamin A plays a crucial role in organizing the cytoskeleton by crosslinking actin filaments into a three-dimensional network, which maintains cell shape, enables cellular movement, and facilitates intracellular transport. Filamin A functions extend to mechanotransduction and signal transduction pathways, which are vital for cellular responses to mechanical stimuli and external signals. Filamin A interacts with numerous proteins, including integrins and growth factor receptors, influencing cell adhesion and migration. Filamin A′s ability to form homodimers enhances structural integrity and functional versatility, making Filamin A a key player in both muscle and non-muscle tissues. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, NIH/3T3 cells, using Filamin A Rabbit Monoclonal Antibody (EAB22120) at 1:4000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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