| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC | 34 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | OGN Rabbit Polyclonal Antibody detects endogenous levels of OGN protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
OGN also known as Osteoglycin, Mimecan, osteoinductive factor is a member of the small leucine-rich proteoglycan (SLRP) family, which plays a crucial role in organizing extracellular matrix and interacts with transforming growth factor beta (TGFβ) to regulate bone formation. Osteoglycin is primarily secreted and found in bone tissues, where Osteoglycin is essential for inducing bone formation in conjunction with TGFβ1 or TGFβ2. The precursor form of Osteoglycin undergoes in situ proteolytic cleavage, resulting in a mature form that is biologically active. This post-translational modification ensures proper functioning of Osteoglycin in bone development and maintenance, highlighting Osteoglycin′s importance in skeletal health and potential implications in bone-related diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3, Mouse liver, Mouse kidney cells, using OGN Rabbit Polyclonal Antibody (EAB22342) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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