| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 44 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NRG1 Rabbit Polyclonal Antibody detects endogenous levels of NRG1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NRG1(Neuregulin 1) also known as SMDF is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. where NRG1 is involved in regulating cell migration, differentiation of neural crest and Schwann cells, and upregulation of acetylcholine receptors at muscle fibers during neuromuscular junction formation. NRG1 gene produces multiple splice variants, each with unique structural features and functions, contributing to diverse roles in neural development and synaptic plasticity. NRG1 has been implicated in various neurological disorders, including schizophrenia, highlighting NRG1′s importance in both normal physiology and disease states. Multiple isoforms of NRG1, characterized by EGF-like domains and varying glycosylation patterns, underscore the complexity of regulatory mechanisms and interactions within the cellular environment. |
| Product Image Gallery | |
 Western blot analysis of extracts on SKOV3 cells, using NRG1 Rabbit Polyclonal Antibody (EAB14321) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human brain tissue, using NRG1 Rabbit Polyclonal Antibody (EAB14321) at 1:100 dilution.
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