| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, FC, ELISA | 45 | Human, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LAMP1 Mouse Monoclonal Antibody detects endogenous levels of LAMP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LAMP-1 also known as CD107a is a glycosylated type I membrane protein that plays a crucial role in maintaining lysosomal function and integrity. LAMP-1 is primarily located on the lysosomal membrane, where LAMP-1 contributes to the regulation of lysosomal pH and protects lysosomal membranes from autodigestion. This localization is vital for cellular homeostasis, as lysosomes are responsible for degrading and recycling cellular waste, and any dysfunction in LAMP-1 can lead to lysosomal storage disorders. LAMP-1 is expressed on the surface of thrombin-activated platelets, suggesting LAMP-1′s involvement in the adhesive and prothrombotic properties of these cells, which is particularly important in the context of wound healing and inflammation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A431, MCF7 cells, using LAMP1 Mouse Monoclonal Antibody (EAB21217) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 45 kDa; Observed band size: 45,120 kDa |
