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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 202 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Integrin β4 (Tyr1510) Rabbit Polyclonal Antibody detects endogenous levels of TIntegrin β4 protein only when phosphorylated at Tyr1510. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Integrin β4 (ITGB4) also known as CD104 is a single-pass type I membrane protein consisting of 1822 amino acids and is primarily expressed in epithelial tissues. ITGB4 associates with Integrin α6 to form a receptor for Laminin, a key component of the extracellular matrix that influences cell behavior, including migration, differentiation, and survival. The interaction between ITGB4 and Laminin is vital for maintaining the structural integrity of epithelial tissues and facilitating communication between cells and their microenvironment. Integrins are heterodimers formed from noncovalently associated transmembrane α and β subunits, play a crucial role in cell adhesion and signaling. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells treated with Na2VO3, using Phospho-Integrin β4 (Tyr1510) Rabbit Polyclonal Antibody (EAB14217) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Phospho-Integrin β4 (Tyr1510) Rabbit Polyclonal Antibody (EAB14217) at 1:100 dilution.
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