IL-13 Rabbit Polyclonal Antibody
Catalog #:EAB14197
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, ELISA 16 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity IL-13 Rabbit Polyclonal Antibody detects endogenous levels of IL-13 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P35225

Entrez Gene ID

3596

Product Description

IL-13(Interleukin-13) is a pleiotropic cytokine that plays a crucial role in immune regulation and inflammation, exhibiting approximately 30% sequence identity with IL-4 and sharing many biological activities. IL-13 is primarily secreted by activated T lymphocytes and significantly influences monocytes, macrophages, and B cells by upregulating CD23 and major histocompatibility complex proteins while downregulating CD14. IL-13 is involved in inhibiting proinflammatory cytokines and chemokines from activated monocytes, as well as stimulating IgE expression on activated B cells, making IL-13 a key player in allergic responses and asthma. IL-13′s structure includes five cysteine residues, which are essential for stability and function, and multiple N-linked glycosylation sites that are critical for biological activity and interaction with receptors.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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