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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 21 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-11 Rabbit Polyclonal Antibody detects endogenous levels of IL-11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-11(Interleukin-11) also known as AGIF is a member of the gp130 family of cytokines. IL-11 plays a crucial role in immune regulation and inflammation, being biologically related to other cytokines such as IL-6, leukemia inhibitory factor (LIF), oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). IL-11 is primarily secreted by stromal cells and is essential for stimulating the proliferation of primitive hematopoietic progenitor cells, which is vital for maintaining healthy blood cell production. Additionally, IL-11 works in conjunction with Flt 3-L to promote the expansion of CD34+ cell populations, which are critical for hematopoiesis. IL-11 exerts effects through the interleukin-11 receptor, IL-11R, composed of an IL-11 receptor-specific chain, IL-11Rα, and gp130, a common signal transducing component for several related receptors. |
| Product Image Gallery | |
 Western blot analysis of extracts on Human plasma cells, using IL-11 Rabbit Polyclonal Antibody (EAB14196) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human pancreas tissue, using IL-11 Rabbit Polyclonal Antibody (EAB14196) at 1:100 dilution.
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