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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 28 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IGFBP1 Rabbit Polyclonal Antibody detects endogenous levels of IGFBP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP1 plays a significant role in modulating IGF bioavailability by binding and influencing distribution in the extracellular environment. IGFBP1 regulation is particularly important as insulin production negatively regulates IGFBP1, making IGFBP1 a key player in metabolic processes and fetal development. IGFBP1 gene expression is notably high during fetal liver development and responds to nutritional changes and diabetic conditions, highlighting IGFBP1′s importance in growth regulation and metabolic health. IGFBP1 interacts with other IGFBPs, such as IGFBP2, which may function as a chaperone for IGFs, and IGFBP3, the most abundant IGFBP that complexes with a significant portion of serum IGFs. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7 cells, using IGFBP1 Rabbit Polyclonal Antibody (EAB14175) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human liver tissue, using IGFBP1 Rabbit Polyclonal Antibody (EAB14175) at 1:100 dilution.
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