TRPA1/ANKTM1 Rabbit Polyclonal Antibody
Catalog #:EAB14068
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IF/ICC, ELISA 128 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000   
IF/ICC=1:50-300 
Product Information
Conjugate Unconjugate
Specificity TRPA1/ANKTM1 Rabbit Polyclonal Antibody detects endogenous levels of TRPA1/ANKTM1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

O75762

Entrez Gene ID

8989

Product Description

TRPA1 also known as ANKTM1 is a crucial ion channel that plays a significant role in sensory transduction, particularly in nociceptors and hair cells. TRPA1 is primarily located in the plasma membrane of sensory neurons and inner ear hair cells, where TRPA1 is essential for detecting environmental stimuli such as noxious cold temperatures and irritating compounds like garlic and mustard oil. TRPA1 localization in these cells is vital because TRPA1 allows for rapid response to potentially harmful stimuli, contributing to pain perception and mechanotransduction. Furthermore, TRPA1 activation is linked to calcium influx, which is critical for various cellular signaling pathways.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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