| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 26 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TREM1 Rabbit Polyclonal Antibody detects endogenous levels of TREM1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TREM1(Triggering receptor expressed on myeloid cells 1) also known as CD354 is a receptor belonging to the Ig superfamily that is expressed on myeloid cells. TREM1 plays a crucial role in the immune response by amplifying inflammation and promoting the activation of myeloid cells, particularly monocytes and neutrophils. TREM1 is selectively expressed on blood neutrophils and a subset of monocytes, but not in lymphocytes or dendritic cells, highlighting its specific involvement in innate immunity. TREM1 is a glycoprotein that undergoes post-translational modifications, including glycosylation, which is essential for stability and function; deglycosylation can lead to a reduction in predicted molecular mass. TREM1 forms complexes with DAP12, a signaling adaptor that enhances activating capabilities, thereby playing a significant role in the inflammatory response to pathogens. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, THP-1, Mouse heart cells, using TREM1 Rabbit Polyclonal Antibody (EAB14063) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human brain tissue, using TREM1 Rabbit Polyclonal Antibody (EAB14063) at 1:1000 dilution.
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