| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 31 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TPI1 Rabbit Polyclonal Antibody detects endogenous levels of TPI1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TPI1 also known as TIM, TPI is a crucial enzyme in the glycolytic pathway, facilitating the reversible conversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate, which are essential intermediates in glucose metabolism. This enzymatic activity is vital for energy production, as TPI1 plays a key role in the generation of pyruvate and ATP from glucose, thereby supporting cellular respiration and energy homeostasis. TPI1 is predominantly located in the cytosol, where TPI1 participates in the glycolytic process, and proper functioning is critical for maintaining metabolic balance. Mutations or deficiencies in TPI1 can lead to significant metabolic disorders, including non-spherocytic hemolytic anemia and other serious health issues, underscoring TPI1′s importance in both normal physiology and disease states. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, HepG2, Mouse brain cells, using TPI1 Rabbit Polyclonal Antibody (EAB14058) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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