| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 33 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TNFSF10/TRAIL Rabbit Polyclonal Antibody detects endogenous levels of TNFSF10/TRAIL protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TRAIL also known as TNFSF10, CD253 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. TRAIL plays a crucial role in regulating apoptosis, which is the process of programmed cell death essential for maintaining cellular homeostasis and immune system function. anti-TRAIL antibody (RIK-2) selectively induces apoptosis in cancer cells while sparing normal cells, making TRAIL a potential target for cancer immunotherapy. TRAIL functions by binding to its specific receptors, leading to the activation of apoptotic signaling pathways, which can trigger cell death in tumor cells. The targeted apoptosis-inducing properties of TRAIL highlight its importance in therapeutic strategies aimed at eliminating malignant cells without harming healthy tissue. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293, HuvEc cells, using TNFSF10/TRAIL Rabbit Polyclonal Antibody (EAB14055) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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