| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 48 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TNFR2 Rabbit Polyclonal Antibody detects endogenous levels of TNFR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TNFR2 also known as TNF-R2, TNFRSF1B is a member of the TNF-receptor superfamily. TNFR2 plays a crucial role in mediating the effects of tumor necrosis factor (TNF), a key cytokine involved in inflammation and immune responses. This receptor is primarily expressed on immune cells and is essential for regulating cell survival, proliferation, and differentiation. TNFR2 signaling is associated with anti-apoptotic pathways, which can influence the outcome of various immune responses and contribute to the pathogenesis of autoimmune diseases and cancer. The interaction of TNFR2 with TNF can lead to the recruitment of various signaling molecules, including TRAF2 and TRAF1, which are pivotal for downstream signaling cascades that promote cell survival and inflammatory responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on HT29, NIH/3T3, K562 cells, using TNFR2 Rabbit Polyclonal Antibody (EAB14053) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using TNFR2 Rabbit Polyclonal Antibody (EAB14053) at 1:200 dilution.
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