| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 120 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Toll-like receptor 8/TLR8 Rabbit Polyclonal Antibody detects endogenous levels of Toll-like receptor 8/TLR8 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TLR8(Toll-like receptor 8) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR8 is primarily located in the endosomal compartments of immune cells, where TLR8 detects pathogens and triggers signaling pathways that lead to the production of pro-inflammatory cytokines. The proper functioning of TLR8 is vital for the host′s defense against viral infections, as TLR8 helps to activate the NFκB signaling pathway, which is essential for mounting an effective immune response. Dysregulation of TLR8 can lead to inadequate immune responses or excessive inflammation, highlighting TLR8′s importance in maintaining immune homeostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse liver cells, using Toll-like receptor 8/TLR8 Rabbit Polyclonal Antibody (EAB14432) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 120 kDa; Observed band size: 150 kDa |
